The induction of malignant melanomas in Syrian white hamster by neonatal exposure to urethan.

The Induction of Melanotic Tumors Resembling Cellular Blue Nevi in the Syrian White Hamster by Cutaneous Application of 7,12-Dimethylbenz[a]anthracene*

Melanotic tumors resembling cellular blue nevi of man were induced in the Syrian white hamster by single and multiple applications of 7,1~-dimethylbenz[a]anthracene (DMBA). Histologically they resembled the melanotic tumors produced under similar experimental conditions in the Syrian golden hamster. They showed great variations in pigment content from almost nonpigmented to heavily pigmented tu...

Spontaneous differentiated squamous cell carcinoma of cheek pouch in a Syrian hamster

A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. In histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. Vacoulation o...

Distribution of the serum proteins of Syrian hamster as revealed by Starch gel electrophoresis

Interphase Death of Chinese Hamster Ovary Cells Exposed to Accelerated Heavy Ions

Introduction: Heavy ions are nucleus of elements of iron, argon, carbon and neon that all carry positive electrical charges. For these particles to be useful in radiotherapy they need to accelerated to high energy by more than thousand mega volts. Also the cosmic environment is considered to be a complicated mixture of highly energetic photons and heavy ions such as iron. Therefore, the health ...

Multipotential carcinogenesis with urethan in the Syrian golden hamster.

17rethan in the drinking water (0.~2-0.4 per cent) was administered to 5to 7-weekold Syrian golden hamsters and continued for 4~ weeks with an 8-week interval between the 40th and 48th week. This t rea tment has been found to give rise to melanotic tumors of the skin, papillomas and carcinomas of the forestomach, adenomatous polyps of the cecum, pulmonary adenomatosis, m a m m a r y tumors, hep...